Causes of Iron Deficiency
Iron has both a storage pool and a functional pool. Iron deficiency can be absolute (the body’s iron store is empty) or functional (when the release of iron is compromised).
Causes of Iron Deficiency
Causes of Iron Deficiency
AI gastritis
Bariatric surgery
PPIs
Anti-H2
H pylori
Hookworm
infection
Bleeding
Oedema
Coeliac disease
Inadequate intake
Vegetarian/vegan diet Malnutrition
Increased body needs
Infants/ preschoolers Pregnancy EPO treatment Elite athletes
Chronic blood loss (without anaemia)
GI cancers Donations Heaves menses NSAIDs Haematuria Coagulopathy Steroids
Having certain chronic diseases*
Inflammatory bowel disease (IBD) Chronic heart failure Chronic kidney disease Celiac disease
*block iron transporters and reduce iron absorption, causing functional iron deficiency.
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REFERENCES:
Al-Naseem, Abdulrahman, et al. “Iron deficiency without anaemia: a diagnosis that matters.” Clinical Medicine 21.2 (2021): 107
Anand, Inder S., and Pankaj Gupta. “Anemia and iron deficiency in heart failure: current concepts and emerging therapies.” Circulation 138.1 (2018): 80-98.
